Thomas J. Goodwin, PhD – NASA cellular physiologist (Retired), pioneer and authority in 3D biology, tissue engineering, bioelectromagnetic field effects, and synthesized tissue growth. Dr. Goodwin was theManager of the Disease Modeling and Tissue Analogues Laboratory at the NASA Johnson Space Center and Lead Scientist for the Oxidative Stress and Damage research discipline for more than 15 years.Known for 30 years of work in 3D tissues for study of human physiology and tumor biology, 3D modelsas microbial hosts for infectious disease, and research into effects of ultra-low frequency electromagnetic fields on human tissues. Dr. Goodwin is Honorary President and Chair of the Personalized Medicine panel of the European Society of Translational Medicine (EUSTM). He holds adjunct positions at the University of Texas Medical School, Galveston Texas, Dept. of Surgery, Division of Cardiothoracic Surgery, the University of Houston, Dept. of Health and Human Performance, and is an Adjunct Scientistat the Texas Biomedical Research Institute and the Southwest National Primate Research Center which is sponsored by the National Institutes of Health. He has authored or co-authored over 66 peer reviewarticles, five book chapters on three-dimensional biology and personalized spaceflight medicine, has been awarded 23 U.S. patents, on 3D biology and human physiology, and is the recipient of more than 70 NASA Scientific and Technical awards.
Dr. Goodwin’s research focuses on cell physiology and organ tissue bioengineering, development of ex vivo physiological 3D systems, and the three-dimensional biology of human and animal cells. Complexrecapitulated tissues may serve as surrogates for studies of tumour physiology, viral, and bacterial infectivity, genomic responses to a myriad of cellular conditions including genomic modulation andregulation due to chemical, physical, and environmental stimuli such as may be seen on the Earth and in the microgravity environment and as a platform to study man-machine interfaces. Recent papers includethe co-authorship of Personalized Medicine in Human Space Flight: Using Omics Based Analyses toDevelop Individualized Countermeasures that Enhance Astronaut Safety and Performance, published inthe journal Metabolomics in 2013, Three-Dimensional Normal Human Neural Progenitor Tissue-Like Assemblies: A Model of Persistent Varicella-Zoster Virus Infection”, PLoS Pathogens 2013, and 3DTissue-like Assemblies: A Novel Approach to Investigate Virus–Cell Interactions, Methods 2015.
Goodwin, T.J.; Christofidou-Solomidou, M. Oxidative Stress and Space Biology: An Organ-Based Approach. Int. J. Mol. Sci. 2018, 19, 959